NanoFCM Co., Ltd. supplies advanced scientific instrumentation, allowing the measurement of biological and synthetic substrates, such as extracellular vesicles, nanoparticle carriers, virus, mitochondria and gold nanoparticles to customers across Europe. It is located in Medicity, a biotech incubator in Nottingham, UK.

NanoFCM Co., Ltd.’s parent company, NanoFCM Inc., is headquartered in Xiamen, Fujian province, China. It has developed nano-flow cytometry out of Professor Xiaomei Yan’s work at Xiamen University. This technology has the unique ability to perform multiple parameter analysis on sub-micron particles, which are typically too small to be detected by conventional and micro flow cytometry. In addition to the assessment of fluorescent probes on small particles, nano-flow cytometry measures particle size, size distribution and concentration similarly to a particle analyser, and with the accuracy & resolution of electron microscopy.

The NanoAnalyzer platform offers a flexible, high throughput solution to both academic and private research organisations working on nanoparticle entities. Operating very similarly to a conventional flow cytometer, it lets the operator screen for a wide array of biological markers, whether they are present at the surface or inside the particle. Fluorescence-based detection can perform using a vast array of fluorophores already commercially available, and familiar staining protocols. By simultaneously measuring the scatter signal for each particle, it is possible to derive the size characteristics of each subpopulation, as well as their absolute concentration.